http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1322073-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06043 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-20 |
| filingDate | 1987-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1993-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9d4d35d611b4b79f23fa7289acda10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0ab4dab125161c75e22e755ff0bde8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba384e142e0cd7a373f0232586e797e2 |
| publicationDate | 1993-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1322073-C |
| titleOfInvention | Thiol-carboxylic acid derivatives |
| abstract | ABSTRACT Novel compounds of the formula (I), processes for their preparation and their use as collagenase inhibitors are described: (I) in which R1 is hydroxy; alkoxy; aryloxy; aralkyloxy; -NR6R7 where R6 and R7 are hydrogen or alkyl, or R6 and R7 together with the N-atom to which they are bonded form a 5- to 7-membered ring with an optional heteroatom; -NHCH(R8)COR9 where R8 is hydrogen; alkyl optionally substituted by hydroxy, alkoxy, -NR6R7, quanidine, CO2H, CONH2, SH, or S-alkyl; or CH2-AR where Ar is optionally substituted aryl; and R9 is hydroxy, alkoxy or -NR6R7. R2 is hydrogen or acyl. R3 is C3-6 alkyl. R4 is hydrogen; alkyl; -CH2R10 where R10 is optionally substituted phenyl or heteroaryl; or -CH(R12)O-R11 where R11 is hydrogen; alkyl; or -CH2Ph where Ph is optionally substituted phenyl; and R12 is hydrogen or alkyl. R5 is hydrogen; alkyl; or -CH(R13)COR14 where R13 is hydrogen or alkyl; and R14 is hydroxy, alkoxy or -NR6R7. |
| priorityDate | 1986-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 223.