| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b9f373878f16dc291ff597162e9b344 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C50-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C50-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C46-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-252 |
| filingDate |
1988-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82fbd31297ec06467ccaa57bd30674ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba4bb1112abbbc4df2268530e78f23d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b9e7ba82b1365cfdf3dc35bd5b57aea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40695bb456507e694ef9bdc6752c7b82 |
| publicationDate |
1993-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1315775-C |
| titleOfInvention |
4-demethoxy-4-amino-anthracyclines |
| abstract |
ABSTRACT Anthracycline glycosides of the general formula (I): I wherein R1 represents a hydrogen atom or a hydroxyl group, one of R2 and R3 represents a hydrogen atom and the other of R2 and R3 represents a hydrogen atom or a hydroxyl group; and pharmaceutically acceptabls acid addition salts thereof are antitumor agents. These glycosides may be prepared from a daunomycinone derivative of formula (II): in which the 4-amino group is protected. 4-Demethoxy-4-amino-daunomycinone (I) and an earlier intermediate in its preparation, 4-demethoxy-4-amino-7-deoxy-daunomycinone (IX), can be diazotised followed by mild reduction to form 4-demethoxy-daunomycinone or 4-demethoxy-7-deoxy-daunomycinone respectively. 4-Demethoxy-daunomycinone can be converted into another antitumor anthracycline glycoside, 4-demethoxy-daunorubicin. |
| priorityDate |
1987-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |