| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J73-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C62-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J73-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-00 |
| filingDate |
1985-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7b6df5ef83dad4c85a44352acf1b8a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3470398c7f74eac750ab6ef66b302cc7 |
| publicationDate |
1993-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1314541-C |
| titleOfInvention |
17.beta.-n-monosubstituted carbamoyl -4-aza-5.- androst-1-en-3-ones |
| abstract |
ABSTRACT OF THE DISCLOSURE 17.beta.-N-monosubstituted carbamoyl or 17.beta.-acyl-4-aza-5.alpha.-androst-1-en-3-ones as 5.alpha.reductase inhibitors of the for-mulae (A) and (B), respectively (A) (B) wherein R is selected from hydrogen, methyl and ethyl and R2 is a branched chain alkyl of from 3-12 carbons, R4 is a branched chain alkyl of from 3-12 carbon atoms or aralkyl selected from benzyl and phenethyl or a heterocyclic selected from 2-or 4-pyridyl, 2-pyrrolyl, 2-furyl or thiophenyl; and R', R" and R"' are each selected from hydrogen and methyl; pharmaceutical formulations of the above compounds are active as testosterone 5.alpha.-reductase inhibitors and are useful for treatment of acne, seborrhea, female hirsutism and in the treatment of benign prostatic hypertrophy. |
| priorityDate |
1984-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |