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filingDate 1987-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1993-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66cb3fcd54bbe9cd8b58737c1f7deceb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36de97aa6cbc0974623fd2ef0a5dcf10
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publicationDate 1993-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1313655-C
titleOfInvention Cis-platinum complexes, a process for the preparation thereof, and pharmaceuticals containing these compounds
abstract BEHRINGWERKE AKTIENGESELLSCHAFT 86/B 029 - Ma 590 Dr. Sn/8n Abstract of the disclosure Cis-platinum complexes, a process for the preparation thereof, and pharmaceuticals containing these compounds Compounds of the general formula I I in which R1 represents a hydrogen atom or an alkyl group of the formula CH3(CH2)n- where n = 0 to 5, R2 represents a hydrogen atom when X is a carbamoyl group, an alkyl group having 1 to 6 carbon atoms, a group, bonded in an ether-like fashion, of the form-ula R3-O-CH2-(CHR4)m-CH2- in which R3 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R4 is a hydroxyl group or an alkyloxy group having 1 to 3 carbon atoms, and m is 0 to 2, represents a group, bonded in an ether-like fashion, of the formula H-(CH2)a-(O-(CH2)b)c- where a = 0 to 4, b = 1 to 4 and c = 1 to 7,or R2 represents a radical, bonded in a O-glycoside fashion of the formula in which R5, R6 and R7, independently of one another, are a hydrogen atom or a hydroxyl group, and R8 is a hydrogen atom, a methyl group or a hydroxy methyl group, X represents a methylene group or a carbamoyl group or a covalent bond between R1 and the 2-carbon atom, A1 and A2 are identical and represent the hydroxyl group, chloride, bromide, iodide, nitrate, acetate or tri-fluoroacetate, or A1 represents sulfate or carbonate and A2 represents H2O or A1 and A2 together represent the dianion of an organic acid such as oxalic, malonic, hydroxymalonic, ethyl-malonic, 1,1- or 1,2-cyclobutanedicarboxylic, phthalic, 3- or 4-carboxyphthalic, 3,4-dicarboxyphthalic or N-(carbamoylmethyl)-iminodiacetic acid, are described, and also a process for the preparation thereof, and a medicament containing these compounds.
priorityDate 1986-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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