| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4826a707782225c8d80626e2273cfaee |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-942
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-865 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-16 |
| filingDate |
1985-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1992-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_337a5b65c3e104c6aa6ca446b83adc94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff0d83a4e947572876687ed40a82d19b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24b866dd27ab5720ac03b78c1d4a5049
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24086647670ca1d259336c47c48f50ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1fb00e16d5759a85c3e35fe3933c3d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_392c5d40cf4bb66c200eba0a9c7bc7f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dbc497d2b114ccb38ee3983e67db565 |
| publicationDate |
1992-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1304022-C |
| titleOfInvention |
Insulin precursors, process for their preparation and process for preparing human insulin from such insulin precursors |
| abstract |
A B S T R A C T Human insulin precursors containing the peptide chain B(1-29)-A(1-21) of human insulin and derivatives thereof with a bridging chain connecting the carboxyl terminus of the B(1-29)-chain with the amino terminus of the A(1-21)- chain are prepared by culturing a yeast host transformed with a replicable expression vehicle capable of expressing a DNA-sequence encoding the insulin precursor. The bridging chain is preferably relatively short and contains preferably from 2 to 8 amino acid residues. The bridging chain must not contain two adjacent basic amino acid residues (Lys or Arg) and has one Lys or Arg connected to the amino terminus of the A(1-21)- chain. Human insulin is prepared from the insulin precursors by in vitro conversion. |
| priorityDate |
1984-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |