| abstract |
ABSTRACT OF THE DISCLOSURE Disclosed are indene compounds of formula I: I wherein R1 is (a) a phenyl group optionally substituted; or (b) a bicyclic aromatic group, such as naphtnalene or quinoline; or (c) a heteroaromatic group selected from thiophene, pyridine and pyrrole, optionally substituted; wherein R2 i3 H, halogen, lower alkyl, benzyl, lower alkylthio, lower alkylsulfonyl, dilower alkylsulfamoyl, acylamino, benzylamino, dilower alkylamino, cyano, pyrrole, dilower alkylpyrrole, trifluoromethyl, methoxy, or tri-fluoromethoxy; wherein R3 is CN, COOR4, -CON(R4)2, or COR4, wherein R4 is a lower alkyl group, and "n" is an integer of 1-3 inclusive. A method for preparing such compounds is also disclosed. The compounds are useful as intermediates in the preparation of pharmacologically-active compounds and are distinguished from prior art compound by their unsuggested structure and utility. |