http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1302410-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d269c8e41f178194d858c230c9f85e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1988-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1992-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88542410d125624bd9aea94d04e67cf9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6ca610705d53d4846492110ae510804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e474837282f8790d9579fb3e7df1dfa9 |
| publicationDate | 1992-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1302410-C |
| titleOfInvention | Dihydropyridine anti-allergic and anti-inflammatory agents |
| abstract | ABSTRACT Dihydropyridine Anti-Allergic and Anti-Inflammatory Agents Compounds of the formula:- (I) wherein R is phenyl or phenyl aubstituted by nitro, halo, C1-C4 alkyl, C1-C4 alkoxy, fluoro(C1-C4)alkoxy, aryl(C1-C4)alkoxy, C1-C4 alkylthio, C1-C4 alkylsulphonyl, hydroxy, trifluoromethyl or cyano; R1 and R4 are H or C1-C6 alkyl, or the two groups form a pyrrolidinyl, piperidino, morpholino, piperazinyl, N-(C1-C4 alkyl)piperazinyl or N-(C2-C4 alkanoyl)piperazinyl group; or R2 is H or C1-C4 alkyl and R1 is C3-C7 cycloalkyl, aryl, indanyl or heteroaryl, or a C1-C4 alkyl group substituted by C3-C7 cycloalkyl, C1-C4 alkoxycarbonyl, aryl or heteroaryl; R3 is OH, C1-C6 alkyloxy, aryl(C1-C4 alkoxy), or NR4R5 wherein each of R4 and R5 is independently H or C1-C6 alkyl, or the two groups form a pyrrolidinyl, piperidinol, morpholino, piperazinyl, or N-(C1-C4 alkyl)piperazinyl group; Y is an alkylene group of from 2 to 8 carbon atoms and X is 1-, 2- or 3-imidazopyridyl or 1-, 2- or 3-imidazopyrimidinyl optionally substituted by C1-C4 alkyl, C1-C4 alkoxy, halo, CF3 or CN; are antagonists of PAF and are useful in the treatment of allergic, inflammatory and hypersecretory conditions. |
| priorityDate | 1987-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.