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publicationDate 1991-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1290896-C
titleOfInvention Method for the removal of the formyl group from an ester of an n-formyl peptide or n-formyl aminoacid
abstract METHOD FOR THE REMOVAL OF THE FORMYL GROUP FROM AN ESTER OF AN N-FORMYL PEPTIDE OR N-FORMYL AMINOACID ABSTRACT OF THE DISCLOSURE A method for the removal of the formyl group from an ester of an N-formyl peptide or N-formyl aminoacid, in which the ester is reacted with urea in the presence of a polar solvent and a strong acid, is disclosed. The method is highly selective and gives a high reaction yield, and can be carried out with the use of reagents which are widely available on the market and of low cost.
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