http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1287350-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8cbc6261d883f27c8339ffb4b4cfeaa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6536 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6544 |
| filingDate | 1986-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1991-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4df06a12c66da1a1893c4357725048f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13237a24d05279c5cb997daf60ae9d3e |
| publicationDate | 1991-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1287350-C |
| titleOfInvention | Bisphosphonic acid derivatives, their production and use |
| abstract | ABSTRACT OF THE DISCLOSURE Novel compounds of Formula I (I) or pharmaceutically-acceptable salts thereof, or pharma-ceutically-acceptable in vivo hydrolyzable esters thereof are provided herein. In such Formula, R1-R11 can be the same or different and stand for hydrogen, a straight, branched or cyclic C1-C10 hydrocarbon radical, phenyl or a phenyl-C1-C4-alkyl radical; n is zero or one, and m is zero, one or two; or R2 and R4 when taken together form an unsubstituted saturated aliphatic 5-, 6- or 7- membered ring or a saturated aliphatic 5-, 6- or 7-membered ring which is substituted with one or more C1-C4-alkyl radicals. Such compounds are valuable in human and veterinary practice by reducing bone resorption and surprisingly also in stimulating bone alkaline phosphatase. A substantial increase in bone mass is actually observed during treatment with such compounds. |
| priorityDate | 1985-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 278.