http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1280755-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9647161fb602828d512f4438d0a865e0 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 1988-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fbcefa9de21af14c2b6bd15119a4f4a |
publicationDate | 1991-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1280755-C |
titleOfInvention | 6,7-dihydro-5,8- dimethyl-9-fluoro-1-oxo-1h,5h- benzo[ij]quinolizine-2-carboxylic acid and derivatives |
abstract | ABSTRACT OF THE DISCLOSURE: The compound 6, 7-dihydro-5, 8-dimethyl-9-fluoro-l-oxo-lH,5H-benzo ¦ij¦ quinolizine-2-carboxylic acid, together with its esters, acyl chlorides, alkylaminoalkyl ester salts and pharmaceutically acceptable carboxylate salts are potent antimicrobial agents with a broad spectrum of activity. In a process for producing this compound, four successive intermediates are created then utilised in the eventual synthesis. The five intermediates are: a) 5-carboxyl-6-fluoroquinaldine; b) 1,2-dihydro-6-fluoro-5-hy-droxymethylquinaldine; c) 6-fluoro-5-methyl-1, 2, 3, 4-tetrahydroquinaldine; and d) diethyl 2-[N-(6-fluoro-5-methyl-1,2,3,4-tetrahydroquinaldinyl)] methylenemalonate. |
priorityDate | 1982-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.