| abstract |
Aroyl substituted dihydro-1,4-thiazines Abstract Compounds of the formula I, I wherein Ar is pyridyl, phenyl or phenyl substituted by halogen, halo-C1-4-alkyl, C1-4-alkoxy or carboxy-C1-4-alkyl, n is zero, one or two,R1 is hydrogen, C1-4-alkyl, heterocyclyl-C2 4-alkyl, amino-C2-4-alkyl, C1-4-alkyl-amino C2-4 alkyl, di2C1-4 alkylamino-C2-4 alkyl or C1-4-alkanoyl, and R2 is hydrogen, carboxy-C1-4-alkyl or C1-4-alkoxy-carbonyl-C1-4-alkyl are disclosed as well as their preparation, pharmaceutical compositions containing the same and the use thereof as antirheumatic agents. |