| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac2c17e532220d91aca9a28ef60f178b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-54 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 |
| filingDate |
1984-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1991-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf09457ea1c0eaab3363db0c6a2001c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7117b3eee2956732b3b10dff06ee7d09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c9081838172b67da77bfa0ccd562fd2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23cb7ddb5cc9e36c7efc458ff840bc00 |
| publicationDate |
1991-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1279575-C |
| titleOfInvention |
Thiazide diuretics for antihypertension without diuresis |
| abstract |
TREATMENT OF HYPERTENSION, COMPOUNDS AND COMPOSITIONS FOR ANTIHYPERTENSION AND DIURESIS ABSTRACT OF THE DISCLOSURE Antihypertension action is achieved without diuresis by administration of a thiazide diuretic in an amount which while being sufficient to achieve antihypertension is insufficient to achieve diuresis. Such administration in a non-diuretic amount is effected in 4-8 consecutive hourly doses to achieve reduction of blood pressure without high urine output. The invention further relates to complexes of thiazides with mixed cation-anion exchange resins, to insoluble basic metal hydroxy thiazide salts, the salts of thiazide with calcium disodium edetate or disodium edetate, to molecular complexes of thiazides with long chain polymers such as hydroxy alkyl cellulose polymers, carboxy methyl cellulose and polyvinylpyrrolidone, to beta-adrenergic blocking amine-thiazide salts and to amiloride thiazide salts. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8618174-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023893-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023894-B2 |
| priorityDate |
1983-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |