http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1278293-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_359b45ab51dbd97bd513b984a50c5ef0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J3-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 1986-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a590980f0748ffa220e63d978c36917 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c114cb9659f95a49643582393bfad66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e59d476292fda2d752a2fe104174f124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7f0f70bb4829c09991f335cc4d8bd03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89d0c2540cbe098f6f4122e8bd1d1a9b |
| publicationDate | 1990-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1278293-C |
| titleOfInvention | Androstane-17 beta-carboxylic acid esters |
| abstract | Abstract The invention refers to compounds havins anti-inflammatory activity characterized by the formula or a stereoisomer thereof, in which formula X1 represents a hydrogen, chlorine, bromine or fluorine atom; X2 represents a hydrogen, chlorine, bromine or fluorine atom; R1 represents .alpha. .beta.-hydroxy group, .alpha. .beta.-chlorine atom or an oxo group; R2 represents a hydrogen atom, a methylene group or an .alpha.- or .beta.-methyl group; R3 represents a hydrogen atom or an acyl group of 1 through 8 carbon atoms; R4 represents a hydrogen atom, a (C1-C5) alkyl group or a phenyl group; R5 represents a hydrogen atom, a (C1-C5) alkyl group or a phenyl group; Y represents either CR7R8, O, S or NR9, where R7, R8 and R9 are selected from hydrogen or from straight or branched hydrocarbon chains having 1-8 carbon atoms or from a phenyl group. R6 represents a hydrogen atom, a methyl group; a phenyl or an alkenyl or cycloalkenyl group option-ally substituted by alkyl, nitro, carboxy, alkoxy, halogen, cyano, carbalkoxy or trifluoromethyl group(s); a (C1-C5) alkyl group substituted by at least one halogen atom; a saturated or unsatur-ated carbocyclic or heterocyclic (O, S, N) ring system containing 3-10 atoms in the ring system; a C1 alkyl group substituted by either one or two alicyclic or aromatic 3,4,5 or 6-membered ring system(s) or one, two or three straight or branch-ed, saturated or unsaturated hydrocarbon chains having 1 through 18 carbon atoms; and represents a single or double bond. The invention also refers to a process and intermediates for the preparation of these compounds, a pharmaceutical preparation con-taining one of the compounds and a method for the treatment of inflammatory conditions. |
| priorityDate | 1985-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.