Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
filingDate |
1986-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b288aa6b3a46bf3b341f6be4836efca4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6b3ba90505e77537a44fa5ef85d5707 |
publicationDate |
1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-1262356-A |
titleOfInvention |
1-carba (dethia) cephalosporin 3-triflate ester antibiotics |
abstract |
ABSTRACT 7.beta.-Acylamino-3-trifluoromethylsulfonyloxy-1-carba 3-cephem-4-carboxylic acid antibiotic compounds, esters and salts thereof, and the corresponding 7-amino and protected 7-amino 1-carbacephalosporins are provided. The 3-trifluoromethylsulfonyloxy-substituted 1-carba-cephalosporins also are useful in a process for prepar-ing 3-halo-1-carbacephalosporins which comprises dis-placing the 3-trifluoromethylsulfonyloxy ester group with halide ion in an aprotic polar solvent. These antibiotic compounds are useful in the treatment of infectious diseases in man and animals and the 1-carbacephalosporin compounds particularly have enhanced potency against infectious and resistant microorganisms. |
priorityDate |
1985-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |