http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1262353-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12 |
| filingDate | 1988-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1262353-A |
| titleOfInvention | Aromatic ketone derivative intermediates for the preparation of antidepressant pyrido [1,4] benzodiazepines |
| abstract | ABSTRACT Disclosed are novel aromatic ketone derivatives of the formula: (IIIb) (wherein Ar is pyridinyl, thienyl, phenyl or substituted phenyl; Z is hydrogen, halogen, alkyl, alkoxy, hydroxy or nitro; alk1 is hydrocarbon chain; and Q2 is -NR1R2, -N=CH-OC2H5 or tetrahydropyranyloxy; R1 and R2 are each alkyl or CO2-alkyl or R1 and R2 together with the adjacent nitrogen atom form 1-piperidinyl, 1-phthalimido, 1-pyrrolidinyl, 4-morpholino, 1-piperazinyl or 4-substituted 1-piperazinyl). The aromatic ketone derivatives are useful as intermediates for producing pyrido(1,4)benzodiazepines of the formula: (I) (wherein Ar and Z are as defined above; Y i hydrogen or substituent on the pyridine ring; and R is hydrogen, alkali metal or -alk1-Q1, Q1 is hydrogen, halo, -NR1R2, N=CH-O-C2H5 or tetra-hydropyranyloxy). Some of the pyrido(1,4]benzodiazepines are useful as antidepressant. |
| priorityDate | 1984-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.