http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1261333-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 |
filingDate | 1984-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c669d88fc3c869ad054420d7d01162b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06d6b46c885f1a616cf934591aa5d53c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76afbafd8475ac4f0f89924670f7ad9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de8292fedbbd250596accfca07e20a51 |
publicationDate | 1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1261333-A |
titleOfInvention | Substituted 5-hydroxy-2,3-dihydrobenzofurans and analogs thereof useful as anti-inflammatory agents |
abstract | Abstract of the disclosure The present invention relates to substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs represented by the following formula: or a pharmaceutically acceptable salt thereof, wherein: m is an integer ranging from 1 to 4; A is (a) phenyl substituted with (R1)q wherein when there are more than one R1 (q>1) R1 can be the same or different from each other and is (1) hydrogen; (2) halo; (3) loweralkoxy; (4) lower alkylthio; (5) lower alkyl sulfinyl; (6) lower alkyl sulfonyl; (7) unsubstituted or substituted phenyl substituted with 1 or 2 radicals selected from a group consisting of loweralkoxy; halo; lowerhaloalkyl; loweralkanoyl; hydroxyloweralkyl and CN;(8) loweralkyl; (9) loweralkenyl; (10) lower alkanoyl; (11) haloloweralkyl; (12) -COOH or -COOC1-6 alkyl; (13) aryl having from 1 to 10 carbon atoms; (14) aryloxy having from 1 to 10 carbon atoms; (15) cyano; (16) hydroxyloweralkyl: (17) halo loweralkanoyl; (18) heteroaryl as defined below; or (19) loweralkanoyloxy; q is an integer ranging from 0 to 5; (b) unsubstituted or substituted heteroaryl selected from a group consisting of: (1) thienyl; (2) benzothienyl; (3) furyl; (4) benzofuryl; (5) pyrryl; (6) indolyl; (7) thiazolyl; (8) benzothiazolyl; (9) thiadiazolyl; (10) benzothiadiazolyl; (11) quinolyl; (12) isoquinolyl; (13) pyridyl; (14) pyrazinyl; (15) tetrazolyl; or (16) triazolyl, the heteroaryl above being substituted with one or more of R1. These compounds were found to be potent topical anti-inflammatory agents. |
priorityDate | 1983-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 173.