| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df67e3cd062c59a425c6e6a1b834dc7e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-808
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-826 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 |
| filingDate |
1986-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb00c3cc528780b2b9b2df18eeb2c9ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51c42a85f0f4cd475237f8538ccf5fb7 |
| publicationDate |
1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1259922-A |
| titleOfInvention |
Method for the isolation and purification of hepatitis b surface antigen |
| abstract |
Improved method for the isolation and purification of hepatitis B surface antigen Abstract The supernatant of engineered yeast cells having produced hepatitis B surface antigen and disrupted in the presence of a polysorbate non-ionic detergent is clarified by addition of urea and adsorbed on colloïdal silica from which the purified antigen is desorbed with a low ionic strength buffer supplemented with urea and a polysorbate non-ionic detergent. |
| priorityDate |
1985-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |