http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1258242-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afd115dec46c157d3739020ebd4d866b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6462 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21073 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 |
filingDate | 1984-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1989-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed0f9b2321e876d39185aff9fde12451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73f934f64d61c5cc73fe423254ab1603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8835faba4e60eb92c3d1d92a42e3c8e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_100779aeb1e4b3199bdabb4b0f54aa56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d47c688052991877200885ff32fa2b0 |
publicationDate | 1989-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1258242-A |
titleOfInvention | Urokinase zymogen and composition containing the same |
abstract | Abstract of the Disclosure There is provided a zymogen of plasminogen activator which is produced by culturing human kidney cells in a culturing medium and recovering from the culture fluid by affinity chromatography using a column of immobilized anti-zymogen antibody. The zymogen is a polypeptide having a single chain with a molecular weight of about 50,000. Although the zymogen itself little exhibits plasminogen activator activity, it mani-fests a significant plasminogen activator activity by catalytic amounts of plasmin. The zymogen has a throm-bolytic ability as high as three times that of a human urinary urokinase, and the zymogen is usable for treating human thrombus. The zymogen can be stabilized by the addition of albumin and thus its stable liophy-lized preparation can be prepared. |
priorityDate | 1983-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 219.