| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9bca43ef2851565a3cbc6e3218c7cce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78463cb811e2656f1313d6af348759b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1eaa46d69512b2c6db74123ac2ed945 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-807 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5438 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 |
| filingDate |
1987-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_950f89609b6592537aebdbff976f1f98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eab427471be0fc468062ad1604fa825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4c7dc511958534fbec2a6f170b63911 |
| publicationDate |
1989-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1256495-A |
| titleOfInvention |
Method for electronic detection of a binding reaction |
| abstract |
ABSTRACT OF THE DISCLOSURE A method is disclosed for detecting the occurrence of a binding or complex-forming reaction between specific substances by utilizing the binding reaction to complete an electrical circuit, and then measuring a change in the elec-trical state of this circuit. In a preferred embodiment, a layer of antigen is coated onto a non-conductive base between a pair of electrically conductive layers superposed on the base. Anti-bodies which react with the foregoing antigen are treated so that they become bound to fine electrically conductive, metallic particles. The electrically conductive particles having antibody bound thereto are then added to the antigen layer deposited on the base and allowed to react therewith. Electrically conductive particles are thereby bound to the base due to the binding reaction between the antigen and antibody to thereby form aggregates of elec-trically conductive particles which bridge the electrically conductive layers and complete the circuit. Such a method is highly useful for the detection of antigens in the blood serum of a human patient. |
| priorityDate |
1986-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |