http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1255666-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-12 |
| filingDate | 1985-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b809c0292909cbc975e537b65192f31b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e16faafa92c8d23936c6fc6cbcbde7d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2728b4e14a7cdd00601a6a7fd7bfb155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4fdd4b695e761e5acd7b6141185a731 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ef6dbc4d6966ae0a668f0b2e52fddb2 |
| publicationDate | 1989-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1255666-A |
| titleOfInvention | Phenethanolamine compounds |
| abstract | A B S T R A C T PHENETHANOLAMINE COMPOUNDS The invention provides compounds of the general formula (I) (I) wherein Ar represents a phenyl group optionally substituted by one or more substituents selected from halogen atoms, or C1-6 alkyl, -(CH2)qR, [where R is hydroxy, C1-6 alkoxy, -NR3R4 (where R3 and R4 each represents a hydrogen atom, or a C1-4 alkyl group, or -NR3R4 forms a saturated heterocyclic amino group which has 5-7 ring members and optionally contains in the ring one or more atoms selected from -0-or -S- or a group -NH or -N(CH3)-), -NR5COR6 (where R5 represents a hydrogen atom or a C1-4 alkyl group, and R6 represents a hydrogen atom or a C1-4 alkyl, C1-4 alkoxy, phenyl or -NR3R4 group), -NR5SO2R7 (where R7 represents a C1-4 alkyl, phenyl or -NR3R4 group), -COR8 (where R8 represents hydroxy, C1-4 alkoxy or -NR3R4), -SR9 (where R9 is a hydrogen atom, or a C1-4 alkyl or phenyl group), -SOR9, SO2R9, or -CN, and q represents an integer from 0 to 3], -O(CH2)rR10 [where R10 represents a hydroxy or C1-4 alkoxy group and r is an integer 2 or 3], or -NO2 groups or an alkylenedioxy group of formula -O(CH2)pO-, where p represents an integer 1 or 2; R1 and R2 each represent a hydrogen atom or a C1-3 alkyl group with the proviso that the sum total of carbon atoms in R1 and R2 is not more than 4; X represents a C1-7 alkylene, C2-7 alkenylene or C2-7 alkynylene chain and Y represents a bond, or a C1-6 alkylene, C2-6 alkenylene or C2-6 alkynylene chain with the provisos that the sum total of carbon atoms in X and Y is 2-10 and when X represents C1-7 alkylene, Y represents C2-6 alkenylene or C2-6 alkynylene; and physiologically acceptable salts and solvates thereof. The compounds of formula (I) have a selective stimulant action at .beta.2-adrenoreceptors and are useful, in particular in the treatment of diseases associated with reversible airways abstruction such as asthma and chronic bronchitis |
| priorityDate | 1984-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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