| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59ed4e542ac25d533656ab858082b4db |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
| filingDate |
1985-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77a1b5bcc07ba107cbbae689dd844a26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61e3861e7beef132ff728678eea9b33a |
| publicationDate |
1989-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1249399-A |
| titleOfInvention |
Process for preparing v.sub.1-vasopressin antagonists |
| abstract |
Abstract of the Disclosure Vasopressin derivatives having V1 and oxytocin antagonist activity whose structures are characterized by a Mpa unit at position 1 and a des-Pro unit at position 7 are prepared by peptide synthetic methods also using an oxidative cyclization of a dimercaptan. Representative species thusly prepared are [1-deaminopenicillamine-2-(0-methyl)-tyrosine-7-desproline-8-arginine-9-desglycine]-vasopressin or [1-.beta.-mercaptopropionic acid-2-D-(0-ethyl)-tyrosine-3-isoleucine-4-threonine-7-desproline-8-arginine-9-desglycine]vasopressin. |
| priorityDate |
1984-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |