http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1247601-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc2a22a9271507062ad7e07974d3c58 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-12 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K20-147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-60 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-60 |
filingDate | 1984-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1988-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f7024a7202d8a3fa138dcfe17a39ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95f66c683212e4234b2ce9998c1af460 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c8dc6d8e35fdc0adbf1436c5a0abfe0 |
publicationDate | 1988-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1247601-A |
titleOfInvention | Rat grf and analogs |
abstract | RAT GRF AND ANALOGS ABSTRACT OF THE DISCLOSURE Rat hypothalamic GRF (GH releasing factor) has been synthesized and has the formula: H-His-Ala-Asp-Ala-Ile-Phe-Thr-Ser-Ser-Tyr-Arg-Arg-Ile-Leu-Gly-Gln-Leu-Tyr-Ala-Arg-Lys-Leu-Leu-His-Glu-Ile-Met-Asn-Arg-Gln-Gln-Gly-Glu-Arg-Asn-Gln-Glu-Gln-Arg-Ser-Arg-Phe-Asn-OH. The invention provides synthetic peptides which are extremely potent in stimulating the release of pituitary GH in animals and which have the formula: is a natural amino acid or des-R44; and Y signifies the carboxyl moiety of the amino acid residue at the C-terminus and is the radical -COOR,-CRO,-CONHNHR, -CON(R)(R') or -CH2OR, with R and R' being lower alkyl, fluoro lower alkyl or hydrogen. These peptides or biologically active fragments thereof may be administered to animals, including humans, to stimulate the release of GH and may be used diagnostically. |
priorityDate | 1983-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 207.