http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1246577-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1982-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5990b610991065f11b863ccb0d009cbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4907ee2d1ad8c4e62562bf5c06805da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1807448d3b77c0465f58922cc93698f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c754e90c5f825a88bf0b48e09b5237a6 |
| publicationDate | 1988-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1246577-A |
| titleOfInvention | Camptothecin-1-oxide derivatives and process for preparing same |
| abstract | Abstract New 5- and/or 7-substituted camptothecin-1-oxide derivatives possessing anti-tumor activity with slight toxicity, represented by the general formula: (I) wherein R stands for a hydrogen atom, an alkyl group, a hydroxyl group, an alkoxy group or an acyloxy group and R' for a hydrogen atom, an alkyl group, an aralkyl group, a hydroxymethyl group, an acyloxymethyl group or a carboxy-methyl group, with the proviso that both of R and R' should not be hydrogen atoms. These 5- and/or 7-substituted camptothecin-1-oxide derivatives are prepared by treating the corresponding 5- and/or 7-substituted camptothecins with a peroxidant as N-oxidizing reagent. |
| priorityDate | 1981-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.