http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1246055-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09dd84721e499b843c1e0c78f2e1dfd8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-16 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-16 |
| filingDate | 1981-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0ecb940179ced80be7fc169dc932e35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a58542130dd1f85572501b03785eeb12 |
| publicationDate | 1988-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1246055-A |
| titleOfInvention | N-.omega.-substituted hormonogens of vasopressin and its synthetic analogs |
| abstract | Abstract Novel hormonogen forms of biologically active vaso-pressin and its synthetic analogs having extended half-lives and improved actively are obtained by attaching a side peptide chain containing from 1 to about 3 amino acid residues to the free amino group of an alpha-amino acid residue having a basic side chain. Preferred hormonogens may be represented by the structural formula: (I) wherein A is hydrogen, hydroxy or lower alkoxy, especially methoxy, B is the peptide residue of phenylalanine (Phe) or isoleucine (Ile), D is the peptide residue of glutamine (Gln) or valine (Val), Asn represents the peptide residue of aspara-gine, E represents the peptide residue of proline (Pro), 4-thioproline (4-thioPro) or 3,4-dehydroproline (3,4-dehydroPro) FNHX represents an N-substituted peptide residue of L- or D lysine (Lys) or L- or D- ornithine (Orn), X represents a side peptide chain as previously defined, G is disulfide (-S-S-) or thioether (-CH2S- or -SCH2-) and J is the peptide residue of glycine (Gly), L-Alanine (L-Ala) or D-Alanine (D-Ala). |
| priorityDate | 1980-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.