| abstract |
ABSTRACT OF THE DISCLOSURE Bicyclic phenol ethers of the formula (I):- (I) wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom or an acyl radical, X is an oxygen or sulphur atom or an -NH- group, Y is a -CO-CHR3- group or a -CO-C=CR4R5 group, R3 is a hydrogen atom, a lower alkyl radical, which can optionally be substituted by an aryl radical, or a cycloalkyl radical containing 3 to 7 carbon atoms and R4 and R5, which can be the same or different, are hydrogen atoms, lower alkyl radicals, alkenyl radicals containing 2 to 16 carbon atoms, which can optionally be substituted by an aryl radical, or an aryl radical or R4 and R5, together with the carbon atom to which they are attached, form a cycloalkyl ring con-taining 3 to 7 carbon atoms, and pharmaceutically accept-able, pharmacologically compatible salts thereof have an inhibiting action on anaphylactic reactions of the skin and of the bronchial system, even when administered orally in low dosages. |