| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0f72c66096c79f62800a395826ee550 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10 |
| filingDate |
1983-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1988-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd277aaa265ec3d86a573b24cc41f9ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46af5b0eb198a8193ad4da560eaa32dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c2c02f1f420c0ea0170a8f8c61afeca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3d0f203f177c5e2075f8db899a0129b |
| publicationDate |
1988-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1243306-A |
| titleOfInvention |
Biologically active tripeptide and tetrapeptide alkylamides, processes for the preparation thereof and pharmaceutical compositions containing the same |
| abstract |
ABSTRACT OF THE DISCLOSURE: The invention relates to novel biologically active tripeptide and tetrapeptide alkylamides of the general for-mula (I): (I) wherein R1 is an alkyl radical with 1 to 5 carbon atoms, A is a peptidically bound alanine or proline rest, B is a peptidi-cally bound glycine, alanine or proline rest, n is an integer of 1 or 2 and R2 is an alkylcarbonylamino group with 2 to 12 carbon atoms, an alkenyl radical with 6 to 12 carbon atoms or a benzyloxycarbonylamino group. These compounds show a remark-able inhibitory activity towards the pancreatic and leucocytal elastase and are expected to find use in the treatment of acute pancreatitis, chronical obstructive pulmonary disease (pulmo-nary emphysema) and certain forms of arthrites. The invention also relates to processes for the preparation of the title compounds and to pharmaceutical compositions containing the same. |
| priorityDate |
1982-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |