| abstract |
Abstract: The invention provides imide derivatives of the formula wherein A is a carbonyl group or a sulfonyl group; B is a group of any one of the formulas: (in which E is a methylene group, an ethylene group or an oxygen atom and a full line accompanying a broken line indicates a single bond or a double bond), (in which F is a methylene group or an ethylene group and a full line accompanying a broken line is as defined above) and (in which R1, R2, R3, R4, R5 and R6 are each a hydrogen atom or a methyl group) when A represents a carbonyl group, or B is a 1,2-phenylene group when A represents a sulfonyl group; D is an ethylene group, an ethenylene group or an ethynylene group, of which one or more may be optionally substituted with hydroxyl; and n is an integer of 0, 1 or 2; or the acid addition salts of the above derivatives. These derivatives and salts are useful for the treatment of psychosis. |