abstract |
Abstract of the Disclosure Hybridomas which produce human monoclonal anti-bodies are disclosed. The hybridomas are formed by fusing lymphocytes from individuals with various cancers to an immortal cell line, such as a myeloma, from e.g., a human cell line, or a mouse cell line. The human monoclonal antibodies produced by these hybridomas recognize certain cell surface and intracellular antigens on normal and malig-nant cells. These human monoclonal antibodies are used in the diagnosis of cancer. |