http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1240325-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-46 |
| filingDate | 1979-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d29eaa307eef80bc85f813eeee0bc5e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efb3260b23a14276e8e397b65f362265 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f5e13f008ade55427c431341ed2b4f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71c4ffda647b2c5d743388252fa1273 |
| publicationDate | 1988-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1240325-A |
| titleOfInvention | 4-amino-2-piperidinoquinazolines |
| abstract | A B S T R A C T This invention provides novel antihypertensives which are 4-amino-2-piperidinoquinazolines of the formula (I) wherein R is lower alkyl; and X, which is attached to the 3- or 4- position of the piperidino group, is a group of the formula: (i) -CH2)nCONR1R2, (ii) -O(CH2)nCONR1R2 or (iii) - , wherein n is 0, 1 or 2; and either R1 is hydrogen or lower alkyl, and R2 is lower alkyl; phenyl, lower alkylphenyl, lower alkoxyphenyl or halophenyl; C3-C7 cycloalkyl; or lower alkyl substituted by phenyl, lower alkylphenyl, lower alkoxyphenyl, halophenyl, C3-C7 cycloalkyl, halogen, trifluoromethyl, hydroxy, lower alkoxy, lower alkenyl, lower alkynyl, lower alkoxycarbonyl, phenoxy, lower alkylphenoxy, lower alkoxyphenoxy, halophenoxy or a group of the formula: -NR3R4 wherein R3 and R4 each independently represent hydrogen, lower alkyl, lower alkanoyl or lower alkylsulfonyl; with the proviso that any O, N or halogen atom in R2 is separated by at least 2 carbon atoms from the nitrogen atom to which R2 is attached; or R1 and R2 taken together with the nitrogen atom to which they are attached form a morpholino group optionally substituted by one or two lower alkyl groups, or a 1,2,3,4-tetrahydroisoquinolyl group optionally substituted on the benzene ring portion by one or two lower alkoxy groups; and the pharmaceutically acceptable acid addition salts thereof. |
| priorityDate | 1978-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 171.