http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1239291-A

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filingDate 1987-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f59e792674e87853e991ea65a57156
publicationDate 1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1239291-A
titleOfInvention Apparatus and method for cryopreparing biological tissue for ultrastructural analysis
abstract APPARATUS AND METHOD FOR CRYOPREPARING BIOLOGICAL TISSUE FOR ULTRASTRUCTURAL ANALYSIS This invention relates to apparatus for the cryo-preparation of biological tissue samples for ultrastruc-tural analysis. The use of the apparatus comprises vitrifying a biological tissue sample under cryogenic temperature conditions and ultra low vacuum conditions. The depressurized, vitrified tissue sample is brought to equilibrium in a sample holder at a temperature of less than -140°C. The tissue sample is then dehydrated while maintained in a state of thermal equilibrium. After reaching equilibrium the tissue sample is optionally infiltrated with a degassed resin followed by a polymeri-zation of the resin to form an embedded tissue sample.
priorityDate 1986-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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