| abstract |
ABSTRACT OF THE DISCLOSURE: The invention is related to alkylamides of carboxyalkanoyl peptides, novel compounds with notable inhibition of elastase, of general formula wherein R is alkyl having 1 to 5 carbon atoms or aralkyl, namely phenylethyl, A is a residue of peptidically bound proline or alanine, B is straight bond or a residue of peptidically bound proline or alanine, and X is a methylene chain having 1 to 3 carbon atoms or the -CH=CH-group. The invention is related to a process for produc-ing the novel compounds mentioned as well. The results of pharmacologic testing of these compounds allow to expect the possibility of their pharmacotherapeutic application. |