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filingDate 1984-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bad09e4da2e3a00e68649acdd08c5d69
publicationDate 1988-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1237997-A
titleOfInvention Construction of novel mutant microorganisms
abstract ABSTRACT OF THE DISCLOSURE This invention provides novel mutant strains of microorganisms (e.g., Pseudomonas putida Biotype A) which are capable of converting substrates such as toluene, p-xylene, catechol and 4-methylcatechol to 2-hydroxymuconic semialdehyde or substituted analog of 2-hydroxymuconic semialdehyde quantitatively by the meta (catechol 2,3-oxygenase) pathway. No active 2-hydroxymuconic semialdehyde-metabolizing enzymes are induced in the microorganism, thereby permitting a 2-hydroxymuconic semialdehyde type metabolite to be produced and accumulated in a bioconversion medium containing the microorganism.
priorityDate 1983-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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