http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1229591-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22c3adadb5cc72c5069c682947605aac |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 |
filingDate | 1985-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1987-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83cb2208493e55f8ba46e6d67ddd7a36 |
publicationDate | 1987-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1229591-A |
titleOfInvention | (8s)-8-fluoroerythromycin derivatives, the process for the preparation thereof and the pharmaceutical compositions containing them |
abstract | ABSTRACT (8S)-8-fluoroerythromycin derivatives of formula (I) wherein R is an optionally substituted alkyl, alkenyl or phenyl group R' is hydrogen or methyl and R" is hydrogen or hydroxy, may be prepared by fluorination of the corresponding 8,9-anhydroerythromycin 6,9-hemiketals with perchloryl fluoride in the presence of a compound ROH in strictly anhydrous conditions. The new compounds as well as their pharmaceutically acceptable esters, salts and salt-esters may be employed as the active ingredients of pharmaceutical compositions for antibacterial use suitable for oral administration. |
priorityDate | 1984-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.