| abstract |
ABSTRACT OF THE DISCLOSURE The present invention relates to a process for preparation of cyclic dithiodiacetamides with action inhibiting the malformation or the destruction of the red blood corpuscles due to a genetic modification of the haemoglobin or to parasites, of formula : in which X is a direct bond, an atom of oxygen or of sulfur, a methylene group, an ethylene group or an N-R group, where R is an atom of hydrogen or a lower alkyl group, lower (hydroxy)alkyl group, lower alkanoyl group or a phenyl group ; or their possible pharmaceu-tically acceptable salts ; said process comprising the step of reacting a dithiodiacetate or a mercaptoacetate of lower alkyl with a cyclic secondary amine, optionally oxiding the resulting compound and converting it into a pharmaceutically acceptable salt. |