http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1222764-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_571b8abacacea64d3f7089d0983b8b3b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-80 |
| filingDate | 1984-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1987-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dfa4ce2c92a87f1605271f142a12f12 |
| publicationDate | 1987-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1222764-A |
| titleOfInvention | Hydantoins and their use in medicine |
| abstract | ABSTRACT The hydantoins of formula (I) and their esters, amides, salts and slovates have prostaglandin mimetic and antagonistic properties rendering them useful in medicine. In formula (I) (I) is hydrogen or alkyl; Z1 represents a group of formula -CH2-X-X1-X2 wherein, X is selected from -(CH2)2-, and cis and trans -CH=CH-, X1 is a covalent bond or a straight or branched alkylene chain having 1 to 6 carbon atoms optionally having one of its methylene groups replaced by oxa (-O-) or thia (-S-) provided that at least one carbon atom separates the oxa or thia group from a carboxyl or -CH=CH- group, and X2 is a carboxyl group; and Z2 represents a group selected from -NH-CH2-R and -N=CH-R wherein, R is a group selected from -CO-Y and Y being a group selected from C3 a alkyl, C3-8 alkenyl, phenyl-C1-4 alkyl and phenyl (wherein the phenyl group in both cases is optionally substituted by one or more groups independently selected from alkyl, alkoxy, nitro, halo and trihalomethyl), cycloalkyl of 4 to 8 carbon atoms, and 5- or 6- membered heterocyclic radicals containing at least one heteroatom selected from oxygen, sulphur and nitrogen; and Y1 being a group selected from hydrogen, hydroxy, alkoxy and acyloxy. RMW/KMS/18.01.84 |
| priorityDate | 1983-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 149.