http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1220477-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7c22980d25eb1d159f269bf4aa2c03c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d78cd2835221849f6a74e6349185819 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-04 |
| filingDate | 1985-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1987-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb260ff2bb5e83ac4bf417c0ab2a955f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3513bc42b89965fcde284dcb14106daa |
| publicationDate | 1987-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1220477-A |
| titleOfInvention | Amide derivatives as histamine h-2 receptor antagonists |
| abstract | "Amide Derivatives as Histamine H-2 Receptor Antagonists" The invention relates to amide derivatives which are histamine H-2 antagonists and which inhibit gastric acid secretion. According to the invention there is provided a guanidine derivative of the formula I:- I in which R1 is a hydrogen or 1-10C alkyl, 3-8C cycloalkyl, 4-14C cycloalkylalkyl, 3-6C alkenyl, 3-6C alkynyl, 1-6C alkanoyl, 6-10C aryl, 7-11C aralkyl or 7-11C aroyl, the aryl, aralkyl and aroyl radical being optionally substituted; ring X is a heterocyclic ring as defined in the specification; A is phenylene or 5-7C cycloalkylene, or a 1-8C alkylene into which is optionally inserted one or two groups; D is O or S; and R2 and R3 are hydrogen or a variety of radicals described in the specification: and the pharmaceutically-acceptable acid-addition salts thereof. Manufacturing processes and pharmaceutical compositions are also described. |
| priorityDate | 1981-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 199.