| abstract |
ABSTRACT OF THE DISCLOSURE Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered bio-compatible by including with the polymeric material hyaluronic acid or a salt thereof, The hyaluronic acid may be coated onto the surface of the polymeric material, dispersed through-out the body of the polymeric material, or both. The hyaluronic acid on the surface of the polymeric material may optionally be cross-linked. The biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves, intraocular lenses, vascular grafts, pacemaker leads and the like. |