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filingDate 1984-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1987-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edf6f6b26be13e4c1c345b1ccf3cfd7f
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publicationDate 1987-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1217185-A
titleOfInvention Bronchodilatory azepino [1,2-a] pyrimideine derivatives and acid addition salts thereof and pharmaceutical compositions containing same
abstract ABSTRACT OF THE DISCLOSURE The invention relates to new azepino[1,2-a]pyrimidine derivatives - of the general formula I wherein p = 1, 2 -and acid addition salts thereof which can be prepared by a/ reacting a compound of the formula II with a compound of the general formula III wherein p is as defined above and R7 is alkoxycarbonyl containing 2 to 5 carbon atoms or carboxamido or b/ reacting a compound of the general formula IV wherein R8 is alkyl containing 1 to 4 carbon atoms with a compound of the general formula V wherein R7 is as defined above -and if desired converting a compound of the general formula I to acid addition salt thereof or setting it free from the salt thereof. The new compounds show bronchodilatory activity.
priorityDate 1982-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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