| abstract |
Pharmaceutical Compositions and Method of Producing Alpha2 Antagonism ABSTRACT Pharmaceutical compositions and method of pro-ducing alpha2 antagonism by administering N-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines. These compositions are particularly useful for lowering intraocular pressure and for the treatment of cardiovascular conditions such as, for example, congestive heart failure, angina pectoris, and thrombosis. The compositions and compounds of this invention also produce a reduction in blood pressure and are therefore useful as antihypertensive agents. |