http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1209148-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d78cd2835221849f6a74e6349185819 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-38 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
filingDate | 1983-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1986-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45e2e06273d60108ce71fa5f9ff5c452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4015b01060cec09141c6ce4967f7b90d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff8ce85ab26c28dad0afda6c7e193cbd |
publicationDate | 1986-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-1209148-A |
titleOfInvention | Chemical process for the production of racemic spiro- linked imidazoline- and pyrrolidine-indoline triones |
abstract | ABSTRACT The invention concerns a novel process for the racemisa-tion of unwanted enantiomeric forms of 1'-substituted spiro[imi-dazolidine-4,3'-indoline]-2,2', 5-triones and 1'-substituted spiro[pyrrolidine-3,3'-indoline]-2,2', 5-triones which comprises heating an unwanted enantiomeric form (or a mixture containing an excess of one enantiomer over the other) alone or, more conven-iently, in the presence of a solvent or diluent at a temperature in the range 80 to 280°C. These compounds have the general formula wherein Ra is (2-12C)alkyl, or naphthylmethyl or cinnamyl optionally bearing one or two halogeno substituents, or benzyl optionally bearing one or two substituents independently selected from halogen, (1-4C)alkyl, (1-4C)alkoxy, cyano, nitro and tri-fluoromethyl located in the 2-, 3-, 4- or 5-position of the phenyl moiety; benzene ring A optionally bears one or two substituents independently selected from halogeno, (1-4C)alkyl, trifluoromethyl and nitro; and Q is methylene or imino; but Ra is other than ethyl, n-propyl or unsubstituted benzyl when benzene ring A is unsubstituted and Q is imino. |
priorityDate | 1982-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.