| abstract |
"Pyrrolacetic amides having antiinflammatory acitivity" ABSTRACT OF THE DISCLOSURES N-monosubstituted and N,N-disubstituted amides of the 1-methyl-5-p-toluoylpyrrole-2-acetic acid, which are active as antiinflammatory, analgesic, antipyretic, antisecretive and antitussive agents, are disclosed. These amides are prepared by reacting an amine with an activated derivative of the 1-methyl-5-p-toluoylpyrrole-2--acetic acid of formula wherein X is an activating group suitable for promoting the formation of an amide bond. |