| abstract |
DISCLOSURE OF DISCLOSURE: The invention relates to the preparation of products of general formula I: (I) in which: R1 - optionally substituted thienyl or phenyl, furyl, cycloalkyl, naphthyl, phenyl-phenyl, alkyl or alkenyl; R2 = methyl or ethyl; R3 = H, OH, alkyl, alkenyl, optionally substituted alkynyl, acetyl, hydroxyacetyl, carboxyalkoxy optionally esterified or salified, hydroxy-optionally esterified alkyl; R4 = H, OH, alkyl, alkenyl, alkynyl optionally substituted by amino, alkyl or dialkyl amino, halogen, thioalkyl, alkoxy, trialkylsilyl or cyano; R5 = H or methyl; X = O, hydroxyimino or alkoxyimino; A and B = .alpha.-epoxy or second bond. Products I are useful as medicines, especially because of their remarks anti-glucocorticoid, progestomimetic or anti-progestomimetic, androgenic or antiandrogenic. |