http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1205810-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-655345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4006 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-32 |
| filingDate | 1982-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1986-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85417cce63b4acd8078d32112f2d5ca5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df1e270b1eb0f9840f5a50ba40ba1d9a |
| publicationDate | 1986-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1205810-A |
| titleOfInvention | Process for the preparation of 2-(thien-2-yl)- and 2- (thien-3-yl)-ethylamine derivatives |
| abstract | ABSTRACT . The present invention provides a process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl)-ethylamine derivatives of the general formula:- (I) in which R1, in the 2-, 3-, 4 or 5-position, is a hydrogen or halogen atom, a nitro, carboxyl, cyano or amino group, a linear or branched alkyl or alkoxy radical or a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, the aminoethyl chain is in the 2- or 3-position, R2, R3 and R4, which are the same or different, are hydrogen atoms or heterocyclic or non-heterocyclic aroma-tic radicals, which are optionally mono- or polysubstituted, and Ar is a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, wherein a compound of the general formula:- (II) in which R3 has the above-given meaning and X and Y, and Y, which may be the same or different, are alkyl, alkoxy, aryl, aryloxy, dialkylamino or diarylamino radicals, is condensed with a carbonyl compound of the general formula:- (III) in which Ar and R4 have the above-given meanings, to give a compound of the general formula:- (IV) in which X, Y, Ar, R3 and R4 have the above-given meanings, which is treated with a base of the general formula B?M? to give a carbanion of the general formula:- (V) in which X, Y, Ar, R3 and R3 have the above-given meanings, which is reacted with a carbonyl derivative of the general formula:- (VII) in which R1 and R2 have the above given meanings, to give a compound or the general formula:- (VIII) in which R1, R2, R3, R4 and Ar have the above-given meanings, which is treated with a reducing agent to give a compound of general formula (I). |
| priorityDate | 1981-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.