http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1204763-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-78 |
| filingDate | 1983-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1986-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6995b27860ee4b1ed1e0671dd5a7c5d2 |
| publicationDate | 1986-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1204763-A |
| titleOfInvention | Spiro-3-hetero-azolones for treatment of diabetic complications |
| abstract | ABSTRACT OF THE DISCLOSURE Spiro-oxazolidones, -thiazolidones and -imidazolidones of the formula below are prepared which are useful as aldose reductase inhibitors and as therapeutic agents for the treatment of complications arising from diabetes: I and the pharmaceutically acceptable salts thereof, wherein U is oxygen, sulfur or nitrogen substituted with hydrogen or alkyl having 1-4 carbon atoms; n is zero or one; R is hydrogen or alkyl having 1-4 carbon atoms; W is carbonyl or hydroxymethylene; X is hydrogen, bromo, chloro, iodo, alkyl having 1-4 carbon atoms, di-methyl or (CH2)mQ wherein m is 1 or 2 and Q is phenyl or halo-phenyl, with the proviso that when X is dimethyl, n is one; Y is hydrogen, halo, nitro, trifluoromethyl, alkoxy having 1-4 carbon atoms or alkyl having 1-4 carbon atoms; Z is hydrogen, halo, nitro, trifluoromethyl, alkoxy having 1-4 carbon atoms or alkyl having 1-4 carbon atoms, with the proviso that is either Y or Z is nitro the other is hydrogen. |
| priorityDate | 1982-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.