Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1dfd39878009ed672c93ba0247ee666 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-886 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-00 |
filingDate |
1983-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1986-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c8c965e4da128be46cdb0d1c7a0747b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d69647b2aba913da6a9ce2cce6e04459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dc4efd485e554fa21ec79c160e1990a |
publicationDate |
1986-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-1204070-A |
titleOfInvention |
Biosynthesis of unnatural cephalosporins |
abstract |
ABSTRACT OF THE DISCLOSURE A process for converting a peptide precursor of the ACV type, in which the valine moiety may be replaced by any readily available amino acid,to an unnatural cephalosporin of the type where Rl is H, lower alkyl or functionalizied carboxylic group and R2 is H or lower alkyl,in which the precursor is reacted with cyclase, epimerase and a ring expansion enzyme isolated from a cell-free extract of a prokaryotic organism such as Streptomyces clavuligerus. The three enzymes may be immobilized on a suitable support medium and the conversion may be carried out in a continuous mode. |
priorityDate |
1982-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |