| abstract |
ABSTRACT Novel indole derivatives, processes for their manufacture and their use as medicaments Novel indole derivatives of the general formula I (I) (in which R1 represents H, C1-C6-alkyl or benzyl, R2 represents H, C1-C4-alkyl, free or esterified C1-C4-hydroxyalkyl or free, amidated or esterified COOH or carboxyalkyl, R3 represents H or C1-C6-alkyl, R4 repre-sents H or C1-C6-alkyl and R5 represents H, C1-C6-alkyl, alkenyl, cycloalkyl or cycloalkyl-alkyl optionally sub-stituted by free, amidated or esterified COOH or by optionally substituted phenyl, or C2-C8-di- or poly-methylene attached to another indole group) and physiologically tolerable salts with acids thereof and alkali and alkaline earth metal salts of such COOH-compounds, and processes for the manufacture thereof. The aforesaid novel compounds have .beta.-receptor stimulating activity and also an anti-allergic, anti-phlogistic and analgesic activity and accordingly may be made up with suitable carriers into pharmaceutical preparations. |