| abstract |
ABSTRACT OF THE DISCLOSURE 7?-alkoxycarbonyl-15?,16?-methylene 4-androstene compounds of Formula I (I) wherein R1 is hydrogen or methyl, R2 is alkyl of 1-4 carbon atoms, X is and Y is carbonyl, and the bond between the C-1 and C-2 carbon atoms is a single or double bond, or when the bond between the C-1 and C-2 carbon atoms is a single bond, X can also be when Y is possess valuable pharmacological properties, e.g., as aldosterone antagonists, i.e. they reverse the effect of deoxycorticosterone on the excretion of sodium and potassium. |