http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1200762-A

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filingDate 1982-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1986-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266cb8f03acc7007b6a15d77592fe761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f45af13999c8cd0964b14626a5a6cd81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac431def23558e80fe5a7805351be112
publicationDate 1986-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1200762-A
titleOfInvention Pharmaceutical preparation
abstract ABSTRACT According to the present invention an oral pharmaceutical preparation of acetylsalicylic acid is provided which con-sists of cores containing acetylsalicylic acid as pharma-ceutically active component, which cores are coated with a polymer membrane to the formation of coated granules. The preparation is characterized in that the polymer membrane comprises at least one polymer selected from the group consisting of cellulose acetate phtalate and methyl esteri-fied methacrylic acid polymers having a degree of esterifi-cation of 45-55 %, whereby the amount of such polymer forms 60-45 % of the weight of the membrane, and at least one methyl esterified methacrylic acid polymer having a degree of esterification of 65-75 % and forming 45-25 % of the weight of the membrane, and a plasticizer selected from fatty alcohols and fatty acids forming 4-12 % of the weight of the membrane, whereby the membrane represents 5-12 weight-% of the composition. With this composition a reduced effect on the gastric mucosa as compared with previously known preparations but retaining good absorbtion properties and a controlled release.
priorityDate 1981-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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