abstract |
A B S T R A C T A 6- and/or 7-oxy-trans-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]-quinoline in which the 3-position is substituted by an optionally amidated carboxy group, an optionally etherified hydroxymethyl group, a cyanomethyl group, an alkyl- or aryl-thiomethyl group or a sulfamoylamino or carbamoylanlino group, or a physiologi-cally-hydrolysable and -acceptable ester thereof. The subject compounds are useful as pharmaceuticals, in, particular as prolac-tin secretion inhibitors, dopaminergic agents and dopamine re-ceptor stimulating agents. |