http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1196636-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06086 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
| filingDate | 1982-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1985-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e0fcaae12570c6c29053461a4dcf4b4 |
| publicationDate | 1985-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1196636-A |
| titleOfInvention | Benzazepin-2-ones |
| abstract | Benzazepin-2-ones Abstract of the disclosure The invention concerns angiotensin-converting enzyme (ACE) inhibitors of the formula I (I) wherein RA and RB are radicals of the formula and , respectively, in which Ro is carboxy or a functionally modified carboxy; R1 is hydrogen, lower alkyl, amino(lower) alkyl, aryl, aryl (lower) alkyl, cycloalkyl or cycloalkyl (lower) alkyl; R2 is hydrogen or lower alkyl, R3 and R4, each independently, represent hydrogen, lower alkyl, lower alkoxy, lower alkanoyloxy, hydroxy, halogen, tri-fluoromethyl, or R3 and R4 taken together represent lower alkylene-dioxy; R5 is hydrogen or lower alkyl, and X represents oxo, two hydrogens, or one hydroxy together with one hydrogen; and wherein the carbocyclic ring may also be hexahydro or 6,7,8,9-tetrahydro; salts and complexes thereof; and stereoisomers of all these compounds. They are prepared, for example, by reducing a compound corresponding to the formula I, having an additional double bond located at the carbon atom in 3-position. |
| priorityDate | 1981-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 246.